The Obsessive Compulsive Foundation invites investigators to submit grant applications for the 2005 OCF Research Awards.

We ask that the application address each of the following points (unless the point is not relevant to the work proposed):

1.	Background (prior work making this proposal reasonable and worthwhile) -- no more than a paragraph.
2.	Hypotheses that will be tested.
3.	Methods: a. How will subjects be recruited (what evidence is there that you can recruit the numbers needed in the time-frame proposed)? What is the sample size? b. How will the subjects' diagnoses be established? c. What are the inclusion and exclusion criteria? d. Will subjects be randomized to treatment groups? If not, why not? e. Will assignment be double-blind? If not, why not? f. What are the reliability and validity of the proposed outcome measures? g. Will the raters of outcome be blind to the subjects. treatment group? h. Are the therapists demonstrably trained in the therapy to be studied? i. Is the therapy standardized and will adherence to standard therapy procedures be monitored in any way? j. If CBT or behavioral therapy will be studied, how did you decide on the intensity of treatment (once a week versus more intensive treatment)? k. How are the key variables (e.g., "treatment-resistant," "responder") defined? l. What is the proposed length of the study (including recruitment, treatment and follow-up periods)? m. What statistical methods will be used? Has a statistical consultant advised that these statistical methods are appropriate? Is the statistical power adequate? n. Provide all data and assumptions underlying your power calculations, which should be shown.
4.	What is the intended use of the results?
5.	What is the publication plan?
6.	What funding has already been obtained for this proposal, and from what source or sources?
7.	How will the results improve our understanding of: a. The etiology of OCD, b. The epidemiology or clinical picture of OCD, c. The pathophysiology of OCD, or d. The treatment of OCD.
8.	Proposed duration of study (one-year maximum).
9.	Name of Applicant Organization.
10.	If study involves humans, copies of the Informed Consent and the Institutional Review Board approvals are required from each site involved, before payment.
11.	If study involves human gene therapy, you must submit a copy of the NIH Recombinant DNA Advisory Committee (RAC) review or waiver of review.
12.	Overhead, indirect and travel costs are not awarded.

The deadline for submission is January 15, 2005. Send one (1) original and fifteen copies (15) to Jeannette A. Cole, deputy director, OC Foundation Research Awards Committee, OC Foundation, Inc., 676 State Street, New Haven, CT 06511.

The Obsessive Compulsive Foundation is an international advocacy organization, founded in 1986 by people with OCD who wanted to make it possible for OCD sufferers to be diagnosed and treated effectively. The Foundation's membership included people with OCD, their families and support networks along with mental health professionals who treat and do research into OCD and the OC Spectrum Disorders.

To further its goal of "Effective Treatment for Everyone" the Foundation has awarded $1,143,089 in research grants since 1994. In 2004 the OCF Board of Directors awarded six grants ranging from $29,000 to $46,000.